Physical Properties | | | |
Molecular Weight: 401.85 g/mol | logS: -4.91767 | SlogP: 3.80064 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0788223 | Sterimol/B1: 2.23534 | Sterimol/B2: 2.8466 | Sterimol/B3: 6.25373 |
Sterimol/B4: 8.88692 | Sterimol/L: 19.1902 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 695.508 | Positive charged surface: 376.95 | Negative charged surface: 318.559 | Volume: 369.875 |
Hydrophobic surface: 572.556 | Hydrophilic surface: 122.952 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |