Physical Properties | | | |
Molecular Weight: 400.527 g/mol | logS: -6.88461 | SlogP: 4.3553 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0292732 | Sterimol/B1: 2.0615 | Sterimol/B2: 4.78235 | Sterimol/B3: 5.35414 |
Sterimol/B4: 6.61154 | Sterimol/L: 20.3432 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 690.736 | Positive charged surface: 399.603 | Negative charged surface: 291.133 | Volume: 368.125 |
Hydrophobic surface: 525.061 | Hydrophilic surface: 165.675 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |