Physical Properties | | | |
Molecular Weight: 383.492 g/mol | logS: -3.96649 | SlogP: 3.76094 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0722516 | Sterimol/B1: 2.1535 | Sterimol/B2: 2.59961 | Sterimol/B3: 5.97783 |
Sterimol/B4: 7.6271 | Sterimol/L: 19.3076 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 686.03 | Positive charged surface: 444.348 | Negative charged surface: 241.682 | Volume: 386.375 |
Hydrophobic surface: 572.157 | Hydrophilic surface: 113.873 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |