Physical Properties | | | |
Molecular Weight: 401.576 g/mol | logS: -4.841 | SlogP: 2.3794 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0286008 | Sterimol/B1: 3.04268 | Sterimol/B2: 4.18665 | Sterimol/B3: 4.27674 |
Sterimol/B4: 4.84348 | Sterimol/L: 21.0971 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 657.711 | Positive charged surface: 436.547 | Negative charged surface: 221.164 | Volume: 354.875 |
Hydrophobic surface: 478.314 | Hydrophilic surface: 179.397 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |