Physical Properties | | | |
Molecular Weight: 400.479 g/mol | logS: -3.92272 | SlogP: 1.9624 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0627236 | Sterimol/B1: 3.13956 | Sterimol/B2: 3.56594 | Sterimol/B3: 4.26634 |
Sterimol/B4: 6.4823 | Sterimol/L: 18.8033 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 657.796 | Positive charged surface: 482.88 | Negative charged surface: 174.916 | Volume: 377.625 |
Hydrophobic surface: 501.121 | Hydrophilic surface: 156.675 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |