Physical Properties | | | |
Molecular Weight: 413.477 g/mol | logS: -5.78794 | SlogP: 3.845 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.10769 | Sterimol/B1: 2.12785 | Sterimol/B2: 3.86526 | Sterimol/B3: 3.93392 |
Sterimol/B4: 9.46815 | Sterimol/L: 17.2399 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 674.107 | Positive charged surface: 374.522 | Negative charged surface: 299.585 | Volume: 398.875 |
Hydrophobic surface: 584.235 | Hydrophilic surface: 89.872 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |