Physical Properties | | | |
Molecular Weight: 411.505 g/mol | logS: -5.65222 | SlogP: 3.86784 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0602632 | Sterimol/B1: 2.67029 | Sterimol/B2: 4.11472 | Sterimol/B3: 4.57955 |
Sterimol/B4: 9.24272 | Sterimol/L: 19.3839 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 718.691 | Positive charged surface: 423.835 | Negative charged surface: 290.384 | Volume: 411 |
Hydrophobic surface: 613.902 | Hydrophilic surface: 104.789 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |