Physical Properties | | | |
Molecular Weight: 396.467 g/mol | logS: -6.02872 | SlogP: 2.9626 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0348352 | Sterimol/B1: 2.5354 | Sterimol/B2: 3.58219 | Sterimol/B3: 3.65599 |
Sterimol/B4: 9.36764 | Sterimol/L: 19.6097 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 682.639 | Positive charged surface: 379.415 | Negative charged surface: 298.438 | Volume: 362.375 |
Hydrophobic surface: 500.701 | Hydrophilic surface: 181.938 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |