Physical Properties | | | |
Molecular Weight: 421.569 g/mol | logS: -5.24827 | SlogP: 4.54261 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.108729 | Sterimol/B1: 3.51189 | Sterimol/B2: 4.02275 | Sterimol/B3: 5.06659 |
Sterimol/B4: 11.5169 | Sterimol/L: 16.5032 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 727.104 | Positive charged surface: 498.472 | Negative charged surface: 218.726 | Volume: 407.5 |
Hydrophobic surface: 620.298 | Hydrophilic surface: 106.806 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |