Physical Properties | | | |
Molecular Weight: 496.968 g/mol | logS: -5.28614 | SlogP: 2.5401 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.065548 | Sterimol/B1: 2.30067 | Sterimol/B2: 3.00089 | Sterimol/B3: 6.47404 |
Sterimol/B4: 8.27505 | Sterimol/L: 22.1837 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 764.495 | Positive charged surface: 447.564 | Negative charged surface: 316.931 | Volume: 432.75 |
Hydrophobic surface: 564.128 | Hydrophilic surface: 200.367 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |