Physical Properties | | | |
Molecular Weight: 394.474 g/mol | logS: -7.89317 | SlogP: 4.80417 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0303138 | Sterimol/B1: 3.14522 | Sterimol/B2: 4.04099 | Sterimol/B3: 4.0541 |
Sterimol/B4: 5.12711 | Sterimol/L: 22.7315 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 706.743 | Positive charged surface: 386.525 | Negative charged surface: 301.032 | Volume: 389.75 |
Hydrophobic surface: 619.606 | Hydrophilic surface: 87.137 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |