Physical Properties | | | |
Molecular Weight: 401.419 g/mol | logS: -3.9031 | SlogP: 1.3019 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0265592 | Sterimol/B1: 3.10432 | Sterimol/B2: 3.62763 | Sterimol/B3: 3.95188 |
Sterimol/B4: 4.38077 | Sterimol/L: 23.1688 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 689.332 | Positive charged surface: 452.185 | Negative charged surface: 237.147 | Volume: 362 |
Hydrophobic surface: 476.086 | Hydrophilic surface: 213.246 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |