Physical Properties | | | |
Molecular Weight: 394.427 g/mol | logS: -3.11736 | SlogP: 2.54352 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0233194 | Sterimol/B1: 2.15514 | Sterimol/B2: 3.47992 | Sterimol/B3: 3.76426 |
Sterimol/B4: 8.47488 | Sterimol/L: 20.8434 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 680.625 | Positive charged surface: 404.946 | Negative charged surface: 270.86 | Volume: 365.875 |
Hydrophobic surface: 485.189 | Hydrophilic surface: 195.436 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |