Physical Properties | | | |
Molecular Weight: 382.461 g/mol | logS: -3.72768 | SlogP: 0.70997 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0345786 | Sterimol/B1: 2.37419 | Sterimol/B2: 2.64363 | Sterimol/B3: 4.64188 |
Sterimol/B4: 5.08698 | Sterimol/L: 20.9508 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 623.924 | Positive charged surface: 315.936 | Negative charged surface: 307.988 | Volume: 324 |
Hydrophobic surface: 379.607 | Hydrophilic surface: 244.317 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |