Physical Properties | | | |
Molecular Weight: 454.503 g/mol | logS: -5.70715 | SlogP: 3.15907 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0477349 | Sterimol/B1: 2.55678 | Sterimol/B2: 4.40255 | Sterimol/B3: 4.85372 |
Sterimol/B4: 7.38281 | Sterimol/L: 22.1557 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 724.037 | Positive charged surface: 397.982 | Negative charged surface: 326.055 | Volume: 404.25 |
Hydrophobic surface: 551.632 | Hydrophilic surface: 172.405 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |