Physical Properties | | | |
Molecular Weight: 408.526 g/mol | logS: -6.58112 | SlogP: 5.2084 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0393997 | Sterimol/B1: 2.66241 | Sterimol/B2: 4.21871 | Sterimol/B3: 6.07818 |
Sterimol/B4: 9.434 | Sterimol/L: 18.2564 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 736.951 | Positive charged surface: 494.162 | Negative charged surface: 242.789 | Volume: 397.125 |
Hydrophobic surface: 600.831 | Hydrophilic surface: 136.12 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |