Physical Properties | | | |
Molecular Weight: 394.431 g/mol | logS: -6.13035 | SlogP: 3.9362 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.074206 | Sterimol/B1: 3.40055 | Sterimol/B2: 4.09652 | Sterimol/B3: 4.85941 |
Sterimol/B4: 7.21695 | Sterimol/L: 19.7342 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 647.83 | Positive charged surface: 353.183 | Negative charged surface: 294.647 | Volume: 364.75 |
Hydrophobic surface: 390.404 | Hydrophilic surface: 257.426 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |