Physical Properties | | | |
Molecular Weight: 457.497 g/mol | logS: -5.89816 | SlogP: 4.74827 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.193485 | Sterimol/B1: 2.41722 | Sterimol/B2: 4.12467 | Sterimol/B3: 4.1689 |
Sterimol/B4: 10.4277 | Sterimol/L: 15.2496 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 673.311 | Positive charged surface: 346.555 | Negative charged surface: 326.756 | Volume: 398.75 |
Hydrophobic surface: 604.877 | Hydrophilic surface: 68.434 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |