Physical Properties | | | |
Molecular Weight: 417.465 g/mol | logS: -5.30301 | SlogP: 3.49087 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0332625 | Sterimol/B1: 2.24611 | Sterimol/B2: 3.06471 | Sterimol/B3: 5.69128 |
Sterimol/B4: 6.9863 | Sterimol/L: 21.08 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 684.16 | Positive charged surface: 435.718 | Negative charged surface: 248.442 | Volume: 390.875 |
Hydrophobic surface: 556.574 | Hydrophilic surface: 127.586 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |