Physical Properties | | | |
Molecular Weight: 481.573 g/mol | logS: -4.54576 | SlogP: 1.94814 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0601554 | Sterimol/B1: 2.36666 | Sterimol/B2: 2.89791 | Sterimol/B3: 4.85109 |
Sterimol/B4: 10.3043 | Sterimol/L: 18.5765 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 714.843 | Positive charged surface: 400.097 | Negative charged surface: 314.746 | Volume: 430.5 |
Hydrophobic surface: 532.498 | Hydrophilic surface: 182.345 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |