Physical Properties | | | |
Molecular Weight: 376.79 g/mol | logS: -4.87875 | SlogP: 4.3874 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0178767 | Sterimol/B1: 2.55583 | Sterimol/B2: 3.02445 | Sterimol/B3: 3.75425 |
Sterimol/B4: 6.63385 | Sterimol/L: 17.9874 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 583.914 | Positive charged surface: 268.374 | Negative charged surface: 315.54 | Volume: 295.875 |
Hydrophobic surface: 350.549 | Hydrophilic surface: 233.365 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |