Physical Properties | | | |
Molecular Weight: 431.533 g/mol | logS: -5.4447 | SlogP: 3.51784 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0775723 | Sterimol/B1: 2.11278 | Sterimol/B2: 4.18758 | Sterimol/B3: 4.64805 |
Sterimol/B4: 9.02631 | Sterimol/L: 19.4396 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 726.659 | Positive charged surface: 482.856 | Negative charged surface: 243.803 | Volume: 417.5 |
Hydrophobic surface: 495.969 | Hydrophilic surface: 230.69 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |