Physical Properties | | | |
Molecular Weight: 517.002 g/mol | logS: -6.91952 | SlogP: 4.58604 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0697922 | Sterimol/B1: 3.79655 | Sterimol/B2: 4.10806 | Sterimol/B3: 5.56337 |
Sterimol/B4: 9.85222 | Sterimol/L: 17.8708 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 765.316 | Positive charged surface: 439.168 | Negative charged surface: 326.148 | Volume: 460.625 |
Hydrophobic surface: 656.18 | Hydrophilic surface: 109.136 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |