Physical Properties | | | |
Molecular Weight: 434.537 g/mol | logS: -6.15825 | SlogP: 3.08097 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0200108 | Sterimol/B1: 2.90538 | Sterimol/B2: 3.20186 | Sterimol/B3: 4.16457 |
Sterimol/B4: 4.55458 | Sterimol/L: 26.1118 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 731.339 | Positive charged surface: 445.522 | Negative charged surface: 285.817 | Volume: 387.125 |
Hydrophobic surface: 510.661 | Hydrophilic surface: 220.678 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |