Physical Properties | | | |
Molecular Weight: 404.559 g/mol | logS: -3.50918 | SlogP: 0.2261 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0878314 | Sterimol/B1: 2.79025 | Sterimol/B2: 5.06569 | Sterimol/B3: 5.58949 |
Sterimol/B4: 6.91382 | Sterimol/L: 17.0707 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 695.534 | Positive charged surface: 561.19 | Negative charged surface: 134.344 | Volume: 399 |
Hydrophobic surface: 563.587 | Hydrophilic surface: 131.947 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |