Physical Properties | | | |
Molecular Weight: 421.877 g/mol | logS: -4.5359 | SlogP: 3.42437 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0200219 | Sterimol/B1: 2.3505 | Sterimol/B2: 3.32247 | Sterimol/B3: 3.76934 |
Sterimol/B4: 9.50849 | Sterimol/L: 24.3662 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 749.611 | Positive charged surface: 515.463 | Negative charged surface: 234.148 | Volume: 389.625 |
Hydrophobic surface: 634.093 | Hydrophilic surface: 115.518 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |