Physical Properties | | | |
Molecular Weight: 493.411 g/mol | logS: -7.41238 | SlogP: 5.77792 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0979252 | Sterimol/B1: 3.60171 | Sterimol/B2: 4.64774 | Sterimol/B3: 4.68548 |
Sterimol/B4: 10.1331 | Sterimol/L: 15.5683 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 752.824 | Positive charged surface: 393.116 | Negative charged surface: 359.708 | Volume: 428 |
Hydrophobic surface: 648.266 | Hydrophilic surface: 104.558 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |