Physical Properties | | | |
Molecular Weight: 409.283 g/mol | logS: -6.19075 | SlogP: 4.8632 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0317725 | Sterimol/B1: 2.17007 | Sterimol/B2: 2.6183 | Sterimol/B3: 3.53549 |
Sterimol/B4: 11.2169 | Sterimol/L: 16.5316 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 618.621 | Positive charged surface: 254.004 | Negative charged surface: 364.616 | Volume: 354.375 |
Hydrophobic surface: 525.845 | Hydrophilic surface: 92.776 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |