Physical Properties | | | |
Molecular Weight: 488.992 g/mol | logS: -6.60895 | SlogP: 5.1931 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0249982 | Sterimol/B1: 3.85004 | Sterimol/B2: 5.23861 | Sterimol/B3: 5.24238 |
Sterimol/B4: 5.32812 | Sterimol/L: 23.6111 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 784.81 | Positive charged surface: 434.515 | Negative charged surface: 350.295 | Volume: 438.625 |
Hydrophobic surface: 611.98 | Hydrophilic surface: 172.83 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |