Physical Properties | | | |
Molecular Weight: 484.596 g/mol | logS: -8.43222 | SlogP: 7.1408 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.826274 | Sterimol/B1: 1.97645 | Sterimol/B2: 5.13315 | Sterimol/B3: 7.59539 |
Sterimol/B4: 12.5565 | Sterimol/L: 14.7001 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 817.977 | Positive charged surface: 526.742 | Negative charged surface: 282.022 | Volume: 487.125 |
Hydrophobic surface: 688.954 | Hydrophilic surface: 129.023 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |