Physical Properties | | | |
Molecular Weight: 442.903 g/mol | logS: -7.05029 | SlogP: 4.7021 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0825659 | Sterimol/B1: 3.32383 | Sterimol/B2: 4.71903 | Sterimol/B3: 4.99051 |
Sterimol/B4: 6.59765 | Sterimol/L: 18.1659 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 714.775 | Positive charged surface: 456.553 | Negative charged surface: 258.222 | Volume: 401.5 |
Hydrophobic surface: 554.718 | Hydrophilic surface: 160.057 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |