Physical Properties | | | |
Molecular Weight: 425.53 g/mol | logS: -3.80725 | SlogP: 0.66969 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.034244 | Sterimol/B1: 2.21158 | Sterimol/B2: 3.28706 | Sterimol/B3: 4.28476 |
Sterimol/B4: 8.2783 | Sterimol/L: 21.4324 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 710.541 | Positive charged surface: 397.999 | Negative charged surface: 312.541 | Volume: 371 |
Hydrophobic surface: 449.118 | Hydrophilic surface: 261.423 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |