Physical Properties | | | |
Molecular Weight: 410.495 g/mol | logS: -3.52494 | SlogP: 0.88097 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0400886 | Sterimol/B1: 2.34107 | Sterimol/B2: 2.4483 | Sterimol/B3: 5.03258 |
Sterimol/B4: 5.53257 | Sterimol/L: 20.3284 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 651.019 | Positive charged surface: 358.652 | Negative charged surface: 292.367 | Volume: 356.625 |
Hydrophobic surface: 435.247 | Hydrophilic surface: 215.772 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 3 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |