Physical Properties | | | |
Molecular Weight: 412.442 g/mol | logS: -3.62699 | SlogP: 2.11294 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0307622 | Sterimol/B1: 2.96316 | Sterimol/B2: 4.07334 | Sterimol/B3: 5.6551 |
Sterimol/B4: 6.48257 | Sterimol/L: 20.4262 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 715.444 | Positive charged surface: 495.895 | Negative charged surface: 219.549 | Volume: 386 |
Hydrophobic surface: 522.077 | Hydrophilic surface: 193.367 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |