Physical Properties | | | |
Molecular Weight: 411.501 g/mol | logS: -8.05329 | SlogP: 5.28727 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0444663 | Sterimol/B1: 2.27436 | Sterimol/B2: 2.56915 | Sterimol/B3: 5.59538 |
Sterimol/B4: 9.60104 | Sterimol/L: 20.5132 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 748.593 | Positive charged surface: 408.562 | Negative charged surface: 317.781 | Volume: 412.125 |
Hydrophobic surface: 657.733 | Hydrophilic surface: 90.86 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |