Physical Properties | | | |
Molecular Weight: 460.582 g/mol | logS: -5.39883 | SlogP: 4.28539 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0869573 | Sterimol/B1: 2.13075 | Sterimol/B2: 2.43846 | Sterimol/B3: 6.31228 |
Sterimol/B4: 9.27934 | Sterimol/L: 19.085 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 740.349 | Positive charged surface: 561.755 | Negative charged surface: 178.594 | Volume: 454.25 |
Hydrophobic surface: 580.468 | Hydrophilic surface: 159.881 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |