Physical Properties | | | |
Molecular Weight: 351.495 g/mol | logS: -6.72139 | SlogP: 4.6242 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0208887 | Sterimol/B1: 2.53005 | Sterimol/B2: 3.24717 | Sterimol/B3: 3.97518 |
Sterimol/B4: 5.78262 | Sterimol/L: 24.0166 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 654.354 | Positive charged surface: 419.735 | Negative charged surface: 234.619 | Volume: 330.875 |
Hydrophobic surface: 485.216 | Hydrophilic surface: 169.138 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |