Physical Properties | | | |
Molecular Weight: 380.529 g/mol | logS: -4.6133 | SlogP: 2.8516 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0980779 | Sterimol/B1: 3.28056 | Sterimol/B2: 4.33537 | Sterimol/B3: 4.83707 |
Sterimol/B4: 6.67139 | Sterimol/L: 16.4894 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 626.216 | Positive charged surface: 488.546 | Negative charged surface: 137.67 | Volume: 381.625 |
Hydrophobic surface: 517.452 | Hydrophilic surface: 108.764 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |