Physical Properties | | | |
Molecular Weight: 399.466 g/mol | logS: -4.62358 | SlogP: 4.2139 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0678482 | Sterimol/B1: 2.56252 | Sterimol/B2: 3.37568 | Sterimol/B3: 4.70569 |
Sterimol/B4: 9.43017 | Sterimol/L: 18.1421 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 689.63 | Positive charged surface: 455.251 | Negative charged surface: 234.379 | Volume: 388.5 |
Hydrophobic surface: 597.33 | Hydrophilic surface: 92.3 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |