Physical Properties | | | |
Molecular Weight: 385.479 g/mol | logS: -4.25307 | SlogP: 3.4627 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.128551 | Sterimol/B1: 2.78118 | Sterimol/B2: 2.99302 | Sterimol/B3: 5.29864 |
Sterimol/B4: 9.09709 | Sterimol/L: 15.4473 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 624.944 | Positive charged surface: 384.995 | Negative charged surface: 239.949 | Volume: 354.25 |
Hydrophobic surface: 475.804 | Hydrophilic surface: 149.14 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |