Physical Properties | | | |
Molecular Weight: 410.449 g/mol | logS: -4.28528 | SlogP: 2.5766 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0731604 | Sterimol/B1: 2.75575 | Sterimol/B2: 4.0612 | Sterimol/B3: 4.82241 |
Sterimol/B4: 8.04691 | Sterimol/L: 18.3584 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 658.249 | Positive charged surface: 417.754 | Negative charged surface: 240.495 | Volume: 377.375 |
Hydrophobic surface: 558.8 | Hydrophilic surface: 99.449 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |