Physical Properties | | | |
Molecular Weight: 393.443 g/mol | logS: -3.6415 | SlogP: 3.8388 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0989393 | Sterimol/B1: 3.74275 | Sterimol/B2: 4.80979 | Sterimol/B3: 5.35349 |
Sterimol/B4: 5.41813 | Sterimol/L: 19.2522 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 658.775 | Positive charged surface: 435.216 | Negative charged surface: 223.559 | Volume: 374.5 |
Hydrophobic surface: 543.139 | Hydrophilic surface: 115.636 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |