Physical Properties | | | |
Molecular Weight: 413.319 g/mol | logS: -6.7271 | SlogP: 4.3859 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0207337 | Sterimol/B1: 2.49777 | Sterimol/B2: 4.13021 | Sterimol/B3: 6.90066 |
Sterimol/B4: 7.71963 | Sterimol/L: 16.7839 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 682.404 | Positive charged surface: 372.905 | Negative charged surface: 297.951 | Volume: 365.125 |
Hydrophobic surface: 554.074 | Hydrophilic surface: 128.33 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |