Physical Properties | | | |
Molecular Weight: 404.558 g/mol | logS: -5.18176 | SlogP: 4.40354 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.184701 | Sterimol/B1: 2.42868 | Sterimol/B2: 2.44236 | Sterimol/B3: 9.12243 |
Sterimol/B4: 10.0657 | Sterimol/L: 19.1619 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 755.878 | Positive charged surface: 505.9 | Negative charged surface: 249.978 | Volume: 424.5 |
Hydrophobic surface: 624.497 | Hydrophilic surface: 131.381 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |