Physical Properties | | | |
Molecular Weight: 386.448 g/mol | logS: -3.27404 | SlogP: 2.89634 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0292555 | Sterimol/B1: 2.10156 | Sterimol/B2: 3.14262 | Sterimol/B3: 4.12076 |
Sterimol/B4: 7.16473 | Sterimol/L: 21.4551 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 677.397 | Positive charged surface: 457.363 | Negative charged surface: 220.034 | Volume: 380 |
Hydrophobic surface: 566.561 | Hydrophilic surface: 110.836 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |