Physical Properties | | | |
Molecular Weight: 381.472 g/mol | logS: -4.43349 | SlogP: 4.21057 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0883976 | Sterimol/B1: 2.16371 | Sterimol/B2: 3.36956 | Sterimol/B3: 5.36166 |
Sterimol/B4: 8.52438 | Sterimol/L: 17.5063 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 642.525 | Positive charged surface: 414.571 | Negative charged surface: 227.954 | Volume: 379.125 |
Hydrophobic surface: 529.374 | Hydrophilic surface: 113.151 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |