Physical Properties | | | |
Molecular Weight: 374.451 g/mol | logS: -3.61951 | SlogP: 1.9539 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.107998 | Sterimol/B1: 2.20683 | Sterimol/B2: 3.54226 | Sterimol/B3: 3.83397 |
Sterimol/B4: 11.4523 | Sterimol/L: 12.9879 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 601.777 | Positive charged surface: 378.054 | Negative charged surface: 223.724 | Volume: 334 |
Hydrophobic surface: 356.389 | Hydrophilic surface: 245.388 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |