Physical Properties | | | |
Molecular Weight: 400.497 g/mol | logS: -5.69086 | SlogP: 6.1715 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.147357 | Sterimol/B1: 4.60876 | Sterimol/B2: 5.01113 | Sterimol/B3: 5.36791 |
Sterimol/B4: 6.49994 | Sterimol/L: 17.0726 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 699.43 | Positive charged surface: 412.942 | Negative charged surface: 282.334 | Volume: 402.75 |
Hydrophobic surface: 647.803 | Hydrophilic surface: 51.627 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 1 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |