Physical Properties | | | |
Molecular Weight: 412.509 g/mol | logS: -6.09291 | SlogP: 4.82097 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.112382 | Sterimol/B1: 3.5969 | Sterimol/B2: 4.73667 | Sterimol/B3: 4.92285 |
Sterimol/B4: 8.01942 | Sterimol/L: 20.0156 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 723.638 | Positive charged surface: 434.462 | Negative charged surface: 285.744 | Volume: 422.625 |
Hydrophobic surface: 624.382 | Hydrophilic surface: 99.256 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 1 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |