Physical Properties | | | |
Molecular Weight: 393.487 g/mol | logS: -5.12551 | SlogP: 2.74169 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0701919 | Sterimol/B1: 2.37939 | Sterimol/B2: 3.80643 | Sterimol/B3: 3.82178 |
Sterimol/B4: 11.9568 | Sterimol/L: 18.2149 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 711.806 | Positive charged surface: 439.368 | Negative charged surface: 272.438 | Volume: 396.625 |
Hydrophobic surface: 587.933 | Hydrophilic surface: 123.873 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |